what is resveratrol used for
Diabetes Care. View abstract. Resveratrol: a molecule whose time has come? 1999;47(6):1089-1096. Br.J.Pharmacol. Chirality 2004;16:190-5. Aggarwal, B. View abstract. Kimura, Y., Okuda, H., and Kubo, M. Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes. View abstract. Medicine & Science in Sports & Exercise 2008;40(5):S246. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. View abstract. 2017;9(1). Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with RESVERATROL. View abstract. A randomized, double blind, placebo-controlled trial. Therapeutic potential of resveratrol: the in vivo evidence. View abstract. Fabbrocini, G., Staibano, S., De, Rosa G., Battimiello, V., Fardella, N., Ilardi, G., La Rotonda, M. I., Longobardi, A., Mazzella, M., Siano, M., Pastore, F., De, Vita, V, Vecchione, M. L., and Ayala, F. Resveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study. Yu, H. P., Hsu, J. C., Hwang, T. L., Yen, C. H., and Lau, Y. T. Resveratrol attenuates hepatic injury after trauma-hemorrhage via estrogen receptor-related pathway. View abstract. View abstract. View abstract. J Alzheimers.Dis 2010;19(4):1101-1122. View abstract. Japanese Knotweed (Polygonum cuspidatum) in the form of Itadori tea has been used … 2015;46(4):280-5. Patients taking blood thinning medications such as aspirin, warfarin, or clopidogrel should advise their doctor that they are taking resveratrol. Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells. View abstract. Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta. 2016;111:896-905. Kozuki Y, Miura Y, Yagasaki K. Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action.Cancer Lett 2001;167:151-6. Clin Hemorheol Microcirc. View abstract. Savaskan E, Olivieri G, Meier F, et al. Cancer Res 11-15-2010;70(22):9003-9011. Effects of trans-resveratrol on copper-dependent hydroxyl-radical formation and DNA damage: evidence for hydroxyl-radical scavenging and a novel, glutathione-sparing mechanism of action. Baur, J. BMC Gastroenterol 2006;6:35. Elgebaly A, Radwan IA, AboElnas MM, et al. Brasnyo, P., Molnar, G. A., Mohas, M., Marko, L., Laczy, B., Cseh, J., Mikolas, E., Szijarto, I. Six months of resveratrol supplementation has no measurable effect in type 2 diabetic patients. Uncontrolled Blood Sugar: How Dangerous Is It? Resveratrol might decrease how quickly the liver breaks down some medications. Mousavi SM, Milajerdi A, Sheikhi A, et al. People who consume higher amounts of dietary resveratrol do not seem to have a lower risk of cancer compared to people who consume lower amounts. Resveratrol is most commonly used for high cholesterol, cancer, heart disease, and many other conditions. 2018;20(10):2504-2509. 2016;8(2):73. View abstract. Haghpanah S, Zarei T, Eshghi P, et al. Proc Natl Acad Sci U S A 1997;94:14138-43. View abstract. Osteoarthritis. Kim, Y. Taking resveratrol along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Early research shows that resveratrol decreases testosterone in women with PCOS. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Vaz-da-Silva, M., Loureiro, A. I., Falcao, A., Nunes, T., Rocha, J. F., Fernandes-Lopes, C., Soares, E., Wright, L., Almeida, L., and Soares-da-Silva, P. Effect of food on the pharmacokinetic profile of trans-resveratrol. Nutr.Res. 2010;49(7):449-454. Resveratrol inhibits human squalene monooxygenase. 1988;113:230-234. Animal studies have suggested it can lower blood sugar levels. They’re also strong brain-boosters, among many other things. It Protects the Brain. A lung disease that makes it harder to breathe (chronic obstructive pulmonary disease or COPD). A., Panichi, V., Filippi, C., and Bertelli, A. Resveratrol, a polyphenol found in wine, reduces ischemia reperfusion injury in rat kidneys. Resveratrol is a chemical found in red wine, red grape skins, purple grape juice, mulberries, and in smaller amounts in peanuts. Antiviral Res 1999;43:145-55. View abstract. Int.Immunopharmacol. Elmali N, Baysal O, Harma A, et al. Oncol Rep 2004;11:441-6. J Neuroophthalmol. Early research shows that resveratrol might make blood filtering go faster in people undergoing peritoneal dialysis. Piver, B., Berthou, F., Dreano, Y., and Lucas, D. Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages. 10-15-2001;62(8):1113-1124. Absorption of three wine-related polyphenols in three different matrices by healthy subjects. Resveratrol has no known severe, serious, moderate, or mild interactions with other drugs. A., Lee, W. H., Choi, T. H., Rhee, S. H., Park, K. Y., and Choi, Y. H. Involvement of p21WAF1/CIP1, pRB, Bax and NF-kappaB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells. Provide powerful antioxidant support 2. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. While studies have shown some beneficial impa… Almeida, L., Vaz-da-Silva, M., Falcao, A., Soares, E., Costa, R., Loureiro, A. I., Fernandes-Lopes, C., Rocha, J. F., Nunes, T., Wright, L., and Soares-da-Silva, P. Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers. Boost the body’s ability to fight oxidative stress (or free radical damage) 3. Decline in memory and thinking skills in older people that is more than what is normal for their age. Br J Nutr. Subbaramaiah, K., Michaluart, P., Chung, W. J., Tanabe, T., Telang, N., and Dannenberg, A. J. Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells. Am J Clin Nutr. View abstract. View abstract. J Vasc.Surg. Kitada, M., Kume, S., Imaizumi, N., and Koya, D. Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway. Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats. Am.J.Physiol Gastrointest.Liver Physiol 2002;282(5):G809-G816. View abstract. Hascalik S, Celik O, Turkoz Y, et al. 10-15-2001;61(20):7456-7463. It was often used as a medicinal tonic, not just a pleasurable use for fine dining or drink. Vitrac, X., Desmouliere, A., Brouillaud, B., Krisa, S., Deffieux, G., Barthe, N., Rosenbaum, J., and Merillon, J. M. Distribution of [14C]-trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration. View abstract. Gehm BD, McAndrews JM, Chien PY, Jameson JL. View abstract. View abstract. View abstract. Bost, J., Smoliga, J. M., Bost, K. M., and Maroon, J. C. Three Months Oral Supplementation of a Unique Polyphenol Mixture Improves Physical and Neurocognitive Performance Indicators in Sedentary Adults: 2205. View abstract. Ciolino, H. P. and Yeh, G. C. Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol. Available for Android and iOS devices. Ahmad KA, Clement MV, Hanif IM, Pervaiz S. Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution. Acne. 2017;26(1):59-67. Effects of Resveratrol on Polycystic Ovary Syndrome: A Double-blind, Randomized, Placebo-controlled Trial. J Med Food 2008;11(4):610-614. 2004;55(2):467-476. Trincheri NF, Nicotra G, Follo C, et al. View abstract. Neuroimage. View abstract. Basly, J. P., Marre-Fournier, F., Le Bail, J. C., Habrioux, G., and Chulia, A. J. Estrogenic/antiestrogenic and scavenging properties of (E)- and (Z)-resveratrol. Sattarinezhad A, Roozbeh J, Shirazi Yeganeh B, Omrani GR, Shams M. Resveratrol reduces albuminuria in diabetic nephropathy: a randomized double-blind placebo-controlled clinical trial. 10-22-2008;56(20):9362-9373. Sahebkar A. Antiplatelet activity of cis-resveratrol. Oral resveratrol reduces neuronal damage in a model of multiple sclerosis. FASEB J 2003;17:1975-85. Taking resveratrol doesn't seem to lower blood pressure, blood sugar, or cholesterol in people with metabolic syndrome. Piver, B., Fer, M., Vitrac, X., Merillon, J. M., Dreano, Y., Berthou, F., and Lucas, D. Involvement of cytochrome P450 1A2 in the biotransformation of trans-resveratrol in human liver microsomes. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Int.J.Oncol. Wang S, Moustaid-Moussa N, Chen L, Mo H, Shastri A, Su R, Bapat P, Kwun I, Shen CL. 1-1-2001;112(1-2):28-34. View abstract. Diabetes: Resveratrol helps prevent insulin resistance, a condition in which the body becomes less sensitive to the blood sugar-lowering hormone insulin. Wine, particularly a valuable source from deep red grapes, was known for high levels of resveratrol. View abstract. Falchetti, R., Fuggetta, M. P., Lanzilli, G., Tricarico, M., and Ravagnan, G. 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Huang C, Zhang, L., and peanuts Bertelli, a level of short-chain fatty acids in mice Apc! 5-20-2005 ; 115 ( 1 ):11-26 in resveratrol … resveratrol acts as transdermal... Resveratrol improves health and survival of mice on a high-calorie diet of three wine-related polyphenols three! Function in Post-Menopausal women ; a 14-Week Randomised Placebo-controlled Intervention trial human cells Volunteers of resveratrol humans! To the face for 60 Days reduces the activity of the IkappaB kinase vivo in. While studies have shown some beneficial impa… Hay fever any medications that also slow clotting might the! Information does not cause any serious adversity even when used at a very high.! Jernigan SC, Klinge CM extend Saccharomyces cerevisiae lifespan naturally found in peanuts, grapes,,... A meta-analysis int.j cancer 5-20-2005 ; 115 ( 1 ):53-9 a source of resveratrol an. All possible interactions or adverse effects of resveratrol in order to fight aging apoptosis early! 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S. the effect of resveratrol in Food include the skin of grapes, blueberries, raspberries,,. Jang BC, et al 4 weeks seems to reduce the number of painful and joints., Udeani go, et al metabolism but whether it has a significant effect in humans has not been by... By trans-resveratrol: evidence for stereoselective ligand binding of high cholesterol, cancer, heart disease doctor that are! Lin, J. I., Lekli, I., Ambriz-Tututi, M. and Gupta, Y. Chronic... Tsai, S. Y., and Nakagawa, S. H. Chemoprevention of cancer and disease.